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21235

AAV•Tek™ AEX Buffer Screening Kit: AAV6

Availability

Ships in 6 - 14 Days

Container Size

1EA

Item Count

1 Kit(s)

Price per Item

$1,680.00

21235

AAV•Tek™ AEX Buffer Screening Kit: AAV6

Quantity

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What’s in the Kit
Description
Formulation
Common Applications
Storage

AAV•Tek AEX Buffer Screening Kit: AAV6 is a set of paired equilibration and elution buffers for anion-exchange chromatography of adeno-associated virus serotype 6 (AAV6). The kit is intended for method development and condition screening using strong anion-exchange media.

The kit contains 16 ready-to-use buffers arranged as eight matched pairs: Equilibration Buffer 3A and Elution Buffer 3B, Equilibration Buffer 11A and Elution Buffer 11B, Equilibration Buffer 18A and Elution Buffer 18B, Equilibration Buffer 23A and Elution Buffer 23B, Equilibration Buffer 55A and Elution Buffer 55B, Equilibration Buffer 57A and Elution Buffer 57B, Equilibration Buffer 58A and Elution Buffer 58B, and Equilibration Buffer 59A and Elution Buffer 59B.

  • This product is proprietary to Teknova. Please get in touch if you'd like more information or have any questions.
  • AEX Process Development (AAV6): Develop and refine anion-exchange chromatography conditions specifically for AAV6.

  • Buffer Screening: Systematically evaluate equilibration and elution buffers to optimize binding, wash, and elution parameters.

  • Empty/Full Capsid Resolution: Tune salt and pH conditions to improve separation of empty versus full AAV6 capsids.

  • Resin and Column Scouting: Compare AEX resins and column formats under standardized buffer sets for AAV6.

  • Polishing Step Development: Reduce process- and product-related impurities (e.g., HCP, residual DNA, endotoxin) after capture.

  • Design of Experiments (DoE): Execute scale-down, high-throughput DoE studies for rapid AEX condition optimization.

  • Method Robustness and Range-Finding: Define acceptable operating windows for critical parameters (pH, conductivity, gradient).

  • Process Transfer and Comparability: Support tech transfer and lot-to-lot assessments with standardized buffer panels.

  • Troubleshooting Yield and Purity: Identify conditions to improve recovery, purity, and capsid integrity.

  • Workflow Prototyping: Prototype preclinical purification workflows prior to scale-up.

Storage Temperature
Room Temperature
Shelf Life
1 days

Product Documents

Protocol: AEX Buffer Screening Kit
258 KB
PDF
Data: AEX Buffer Screening Kit
10 MB
PDF
AAV Chromatography Workflow

This product is part of our AAV Chromatography Workflow

Get all the AAV reagents you need from one trusted source, and learn how our AAV·Tek™️ Solutions can save months in your process development.

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