Imidazole solutions are commonly used as buffering and elution reagents in His-tagged protein purification workflows, particularly in Ni²⁺, Co²⁺, or other divalent cation-based IMAC systems. By competing with histidine residues for metal binding sites, imidazole enables selective washing and controlled elution of target proteins.

We offer ready-to-use 1M and 2M imidazole stock solutions at pH 7.5 and 8.0 to support each stage of the purification process. Imidazole solutions may also be used as buffering agents in enzymatic assays and other biochemical applications that require stable pH control.

Our imidazole solutions are supplied as ready-to-use formulations, eliminating in-house preparation and reducing variability across protein purification workflows. Each of our imidazole solutions is manufactured to precise specifications to ensure consistent performance in IMAC applications.

Our imidazole solutions are designed to integrate seamlessly into routine laboratory operations, from small-scale research purifications to method development and process optimization. All products are manufactured under rigorous quality control standards to ensure purity, concentration accuracy, and lot-to-lot consistency. We also support the production of custom imidazole solutions, including modified concentrations, adjusted pH values, blended buffer systems, and alternative container formats to meet specialized research or manufacturing requirements.