Mammalian Cell Culture Shear Protection: 1% Poloxamer 188 (P188) protects suspension cells (e.g., CHO, HEK293) from hydrodynamic shear in shake flasks and bioreactors.

Viral Vector Production: Enhances cell viability and yields during AAV and lentiviral manufacturing by mitigating shear stress with 1% Poloxamer 188.

Electroporation and Transfection Support: Promotes membrane resealing post-electroporation and improves recovery of transfected cells using 1% Poloxamer 188.

Protein and Enzyme Stabilization: Reduces aggregation and surface adsorption during handling, filtration, and storage with 1% Poloxamer 188.

Downstream Processing: Minimizes nonspecific binding to filters and tubing to improve biomolecule recovery using 1% Poloxamer 188.

Flow Cytometry and Cell Handling: Decreases cell clumping and nonspecific adherence in wash buffers with 1% Poloxamer 188.

Microfluidics and Imaging: Limits cell and protein adhesion to channel surfaces, improving flow consistency with 1% Poloxamer 188.

Nanoparticle and Lipid Formulations: Provides steric stabilization and dispersion for nanoparticles and liposomes using 1% Poloxamer 188.

Cryopreservation Workflows: Improves post-thaw cell recovery by mitigating shear during thaw and initial culture with 1% Poloxamer 188.

Filtration and Sterile Processing: Acts as a process aid to reduce product loss from membrane adsorption when using 1% Poloxamer 188.