Nucleic Acid Preservation and Transport: 50mM Tris, 16% (v/v) Ethanol, pH 7.5 provides antimicrobial preservation for DNA/RNA in swab, saliva, and environmental samples, reducing degradation from organisms such as Escherichia coli, Staphylococcus aureus, and Salmonella enterica.

DNA Storage and Shipping: Maintains stable pH for short- to mid-term storage of purified DNA and PCR products while 16% (v/v) ethanol limits microbial growth.

Sample Inactivation for Molecular Testing: Partially inactivates microbes and preserves nucleic acids prior to downstream qPCR/NGS workflows.

Low-Stringency Wash/Pre-equilibration in Nucleic Acid Purification: Used as a mild ethanol-containing buffer during certain silica-based cleanup steps where lower ethanol percentages are required.

Microbiome and Environmental Sample Stabilization: Preserves DNA from field-collected specimens (water, soil, swabs) by buffering pH and inhibiting growth of organisms like Escherichia coli and Staphylococcus aureus.

Amplicon/Library Interim Storage: Temporary holding buffer for sequencing libraries and amplicons to minimize nuclease activity and bioburden between workflow steps.