Upstream pH Control: Used as a base addition for real-time pH control in fermentation and cell culture.

Clean-in-Place (CIP) and Sanitization: Removes soils and bioburden from bioreactors, tanks, tubing, and single-use assemblies.

Endotoxin Reduction/Depyrogenation: Applied to reduce pyrogens and lipopolysaccharides on contact surfaces.

Chromatography Resin Cleaning/Regeneration: Cleans and regenerates Protein A, ion exchange, and HIC resins between cycles.

UF/DF and TFF System Cleaning: Sanitizes ultrafiltration/diafiltration membranes and flow paths to restore performance.

Decontamination and Biofilm Removal: Denatures biomolecules and helps eliminate Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus on equipment surfaces.

Buffer and Process Stream pH Adjustment: Used to titrate and adjust pH of buffers, eluents, and process intermediates.

Alkaline Lysis Reagent Preparation: Diluted from 1M Sodium Hydroxide to prepare solutions for plasmid DNA alkaline lysis workflows.

Nucleic Acid/Protein Denaturation on Surfaces: Helps degrade residual DNA/RNA and denature proteins during surface cleanup.

Waste Stream Neutralization: Neutralizes acidic waste prior to disposal or downstream processing.