pH Adjustment of Buffers and Media: Rapidly adjusts pH during buffer and culture media preparation under sterile, endotoxin-controlled conditions.

Chromatography Column Cleaning and Sanitization: Regenerates resins and columns, removing proteins, nucleic acids, and endotoxins in CIP workflows.

Bioprocess Equipment Cleaning: Sanitizes tanks, tubing, and filtration systems, aiding endotoxin reduction between production runs.

Plasmid DNA Alkaline Lysis: Provides the strong base for cell lysis of Escherichia coli in miniprep and maxiprep workflows.

Neutralization and Titration: Used as a base standard to titrate acids and set precise pH endpoints in analytical methods.

Ion-Exchange Membrane and Filter Regeneration: Restores binding capacity and removes fouling and endotoxins from process membranes.

Endotoxin Inactivation/Depyrogenation: Hydrolyzes and inactivates endotoxins on compatible labware and process surfaces.

Hydrolysis and Saponification: Drives base-catalyzed hydrolysis reactions in sample preparation and analytical chemistry.

General Laboratory Decontamination: Denatures nucleases and decontaminates surfaces and instruments between assays.