SDS-PAGE Sample Preparation: Used to denature proteins and impart uniform negative charge; 20% stock is diluted to prepare Laemmli sample and running buffers.

Protein Solubilization: Utilized to solubilize membrane and hydrophobic proteins for downstream analysis.

Cell Lysis and Nucleic Acid Extraction: Employed in lysis buffers to disrupt cells (e.g., Escherichia coli) and inactivate nucleases during DNA/RNA purification.

Western Blotting: Added to sample and transfer systems to maintain protein denaturation and prevent aggregation.

Enzyme Inactivation: Applied to inactivate proteases and nucleases in biological samples.

Laboratory Decontamination: Used as a detergent for cleaning electrophoresis equipment and glassware to remove protein residues.