Cell Lysis and Viscosity Reduction: Degrades DNA/RNA to lower viscosity in lysates from Escherichia coli, yeast, insect, and mammalian cells for easier handling and processing.

Protein Purification: Removes host-cell nucleic acids prior to chromatography to improve protein yield, purity, and column performance.

Bioprocessing and Downstream Clearance: Reduces residual DNA/RNA in biomanufacturing workflows to meet regulatory limits for host-cell nucleic acids.

Viral Vector and Vaccine Production: Digests contaminating nucleic acids in AAV, adenovirus, and lentivirus preparations to enhance clarity and downstream filtration.

Sample Clarification: Improves filtration and centrifugation efficiency by breaking down nucleic acids that cause clogging and haze.

Structural Biology and EM Prep: Increases protein homogeneity for crystallography and electron microscopy by removing bound nucleic acids.

Assay Preparation: Eliminates background nucleic acids in enzymatic and binding assays to reduce nonspecific interactions.