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MES Solutions

MES Solutions [2-(N-morpholino)ethanesulfonic acid] are zwitterionic and Good's buffers used to help maintain pH levels. These solutions act as buffering reagents between pH 5.5–6.5.
MES Solutions
What are MES buffer solutions?

MES buffer solutions are commonly used in biological systems due to their effective buffering range of approximately pH 5.5-6.7, making them well-suited for applications that require stable, mildly acidic conditions. As part of the Good’s buffer family, MES is designed to exhibit minimal interaction with biological molecules, low metal binding, and limited temperature-dependent pH variation.

 

MES buffer solutions are widely used in enzyme assays, protein purification workflows, cell culture systems, and molecular biology applications where precise pH control is critical. Their compatibility with sensitive biological systems makes them a reliable choice for maintaining consistent experimental conditions.

Why choose Teknova’s MES buffer solutions?

We keep an extensive catalog of MES buffer solutions in stock at various molarities and pHs, supplied as ready-to-use formulations, eliminating the need for buffer preparation. Each formulation is manufactured to precise specifications to ensure consistent buffering capacity and reliable performance.


Our MES buffer solutions are designed to integrate seamlessly into routine laboratory operations, from biochemical assays and protein workflows to process development and quality control. All products are manufactured under rigorous quality control standards to ensure pH accuracy, purity, and lot-to-lot consistency. Teknova also supports custom manufacturing, including adjusted concentrations, modified pH values, and alternative container formats to meet specialized research or manufacturing requirements.

Explore related products

All our products are fully customizable, from formulation to format to fill volume. Our experts can help find the ideal solution for your application and efficiently manufacture your custom product.

Frequently asked questions

You can find answers here for our most commonly asked questions. If you don't find the information you are looking for, get in touch with our team. We're here to help.

MES buffer solutions are used to maintain stable pH in biochemical assays, enzyme reactions, protein purification, and cell culture workflows that require mildly acidic conditions.

 

MES buffer solutions have an effective buffering range of approximately pH 5.5 to 6.7, making them suitable for applications requiring acidic to near-neutral conditions. Learn more in our guide for optimal pH.

 

Good’s buffers are a class of buffering agents designed for biological research, with minimal interference, low toxicity, and stable pH. MES is considered a Good’s buffer because it meets these criteria and performs reliably in biological systems.

Yes. All Teknova MES buffer solutions are supplied pre-formulated and ready to use, eliminating the need for in-house preparation. We can also manufacture a custom solution to your exact specifications with industry-leading turnaround times, tailoring any part of your product, from formulation to container format to documentation and labeling. Learn more about our custom process.

MES buffer solutions should be stored according to product specifications, typically at room temperature. The storage instructions and expiration date for your specific product can be found on your product label.

Find out what’s possible

 

Talk to our consultants today to discover custom solutions that can help you achieve your goals.

 

Get in touch:

1.800.209.4488

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