pH Adjustment and Titration: Used to adjust pH in buffers and media and as a titrant for standard acid-base titrations.

Alkaline Lysis for Plasmid Prep: Employed in plasmid DNA isolation workflows from E. coli to lyse cells and denature chromosomal DNA and proteins.

Chromatography System Cleaning (CIP): Applied to clean and regenerate chromatography columns and fluid paths by removing adsorbed proteins and lipids.

Membrane Stripping: Used to strip antibodies from Western blot membranes for reprobing.

Buffer and Media Preparation: Adjusts the pH of Tris, HEPES, and other laboratory buffers to target values.

Surface and Glassware Cleaning: Removes organic residues and helps reduce bioburden on labware and equipment.

Neutralization and Quenching: Neutralizes acidic solutions and quenches acid-catalyzed reactions.

Hydrolysis/Saponification: Facilitates base-catalyzed hydrolysis of esters and lipids in analytical and preparative workflows.

Nucleic Acid Denaturation: Denatures DNA/RNA for blotting and hybridization procedures.

Ion-Exchange Resin Regeneration: Restores anion exchange resin capacity by converting to hydroxide form.