Cell Lysis for Nucleic Acid Extraction: Efficiently lyses cells and Gram-negative bacteria (e.g., E. coli) to release high-quality DNA/RNA.

RNA Isolation and RNase Inactivation: Denatures proteins and inactivates RNases for high-integrity RNA prep and Northern blot sample preparation.

Membrane Protein Solubilization: Solubilizes membrane proteins for extraction, purification, and downstream analysis.

Polysome/Ribosome Profiling (Ribo-seq): Used in lysis buffers to solubilize membranes while preserving ribosome complexes for gradient fractionation.

Viral Lysis for Nucleic Acid Extraction: Disrupts enveloped viruses to release viral RNA/DNA for detection workflows.

Chromatin and Nuclear Lysis: Disrupts nuclear membranes and chromatin-protein interactions for chromatin and nucleosome preparations.

Inclusion Body Solubilization: Helps solubilize aggregated recombinant proteins from inclusion bodies prior to refolding.

Biofilm and Sample Disruption: Assists in dispersing bacterial biofilms (e.g., Pseudomonas aeruginosa) to improve nucleic acid recovery.