Environmental Monitoring (Passive Air/Settle): Placed open in cleanrooms and controlled environments to capture airborne microorganisms for routine monitoring.

Aseptic Process Simulation (Media Fills): Used during simulation runs to assess airborne contamination risk during critical operations.

Trend Analysis of Microbial Fall-Out: Enables longitudinal trending of ambient bioburden for quality control and release decisions.

Cleanroom and HVAC Qualification/Validation: Supports verification of room classification, airflow patterns, and filtration performance.

Personnel and Process Monitoring: Deployed during set-up, interventions, and routine work to assess operator- and process-associated shedding.

Excursion Investigations: Aids root-cause analysis and corrective action effectiveness checks after environmental monitoring alerts.

Facility Environmental Surveillance: Applied in pharma, biotech, medical device, hospital/compounding, and food/beverage areas to monitor ambient microbiological quality.

Recovery of Nonfastidious Microorganisms: General-purpose cultivation of airborne bacteria and fungi such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Bacillus spp.

Qualification of Cleaning and Disinfection Programs: Verifies the effectiveness of environmental cleaning regimens via fall-out monitoring.

Process Change Control: Used before/after changes to equipment, layout, or HVAC to assess impact on airborne bioburden.